Pearl Trilogy- Small Animal Imaging System for Near-Infrared Fluorescent and Bioluminescent Optical Imaging
28 Sep 2015
2:30pm - 3:30pm
Bilik Mesyuarat, Unit Sumber Haiwan Makmal, Kolej Tun Syed Nasir, UKM (Kampus KL)
Organized by: 
Research Instruments and Laboratory Research Unit, UKM

Presented by: Ichie Osaka, Ph.D. 
Field Application Scientist (International Distribution)


Near‐infrared (NIR) fluorescence offers dramatic benefits for in vivo imaging of small animals, due to the increased depth of penetration and decreased autofluorescence and light scatter that occur at higher wavelengths. The Pearl Trilogy offers affordable small animal near-infrared fluorescence and bioluminescence imaging of mice. This unique, easy‐to-use two-channel system provides exceptional signal‐to‐background ratios and eliminates the need to alter raw data by minimizing the amount of scattered light that reaches the detector. Its large optical dynamic range results in images that without saturation can capture the entire range of signal intensity without the need to change exposure times or post-acquisition background removal. In addition, the Pearl Trilogy features a real-time imaging mode (at 2 frames per second) which allows dynamic imaging of contrast agents. In this presentation, we will discuss the design and performance of the Pearl Trilogy Imager and how it is being used to monitor tumor growth noninvasively in the living animal. Imaging of several NIR fluorescent agents will be discussed, including epidermal growth factor (EGF), 2‐deoxy D‐glucose (2‐DG) and other targeting agents.


Ms Ichie Osaka earned her Ph.D, in Microbiology from University of Kansas, USA. During her time as a graduate student, Ms Ichie worked with various research collaborators, published four peer-reviewed scientific articles and presented research findings at multiple conferences. Upon leaving graduate school, Ms Ichie joined Li-Cor as Field Application Scientist (International Distribution) and has much experience helping users world-wide with integration of Near-infrared (NIR) fluorescence in their research methodology.

Participation is FREE
Limited seats available. Please RSVP by 17th September 2015