How is animal research regulated?

Laws around the world vary. Usually they depend on either a local system (which may be voluntary) or on national controls administered by the government. The UK is the only country in the world to have both systems running at the same time. The strict controls under the Animals (Scientific Procedures) Act 1986 were added to in April 1999 with the introduction of the Local Ethical Review Process for animal research. There are also international regulations such as the European Directive 86/609.